Sunday Conversations May 19 2024 - Are You M.A.D.? with Dr. Anne Maitland

“Are You M.A.D.?”

An axis awry of
Mast cell activation disease,
Autonomic neuropathy and
Disorders of connective tissue


A growing body of evidence is linking heritable disorders of connective tissue, such as Ehlers Danlos Variants, with dysautonomia and mast cell dysfunction, which lead to chronic fatigue, brain fog, irritable bowel symptoms and pain syndromes.  A brief review of the diagnosis and relationships of this clinical triad, MCAD, Autonomic dysfunction, and  Disorders of connective tissue or hEDS. This, in turn, should lead to multi-disciplinary clinical therapies to help right this trio of modern day epidemics.

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